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Nanotoxicology and risk assessment: the state of the art

Programme of the Session


10:00 – 10:15  CE course opening and introduction
10:15 – 11:00

Improving the OECD test guidelines to better address inhalation toxicity assessment of nanomaterials
Ken Moss
United States Environmental Protection Agency, United States

11:00 – 11:45

Principles and Methods for assessing the risk of immunotoxicity associated with exposure to nanomaterials: New WHO guidance
Henk van Loveren
Maastricht University, The Netherlands

11:45 – 12:00 


12:00 – 13:00 

Lunch Break
13:00 – 13:45

Nanomaterials and cancer: what do we know? 
Dawson Kenneth 
School of Chemistry and Chemical Biology, Science Centre South, University College Dublin, Ireland

13:45 – 14:30

Availability of methods for characterising the physical-chemical properties of nanomaterials: implications for hazard identification, read-across and risk assessment 
Juan Riego Sintes 
Joint Research Centre of the European Union, Italy

14:30 – 15:15

Missing elements for regulatory testing and assessments of nanomaterials, and research needs
Camelia Constantin
ECHA - European Chemicals Agency, Finland

15:15 – 16:00

Discussion and Closing of the CEC course

Session Abstract

There are growing concerns that exposure to nanoparticles may pose adverse health impacts, and that the adverse effects are greatly influenced by the small size and size-associated properties of nanoparticles. A decade of nanotoxicology research has clearly established that nanoparticles predominantly induce inflammatory response. Other effects may include adjuvant activity of allergic responses, neurological effects, reproduction effects, and genotoxicity resulting in carcinogenicity; some of these endpoints may in fact depend on inflammatory events occurring after exposure to nanoparticles.  This symposium aims to summarize the state of the art for risk assessment, and identify missing elements and research needs. 
Discussion and Closing of the CE course



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