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Cosmetic safety evaluation in the era of alternatives

Programme of the Session

10:00 – 10:15  CE course opening and introduction
10:15 – 11:00 General principles of cosmetic safety evaluation: the SCCS requests
Gisela H Degen
Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
11:00 – 11:45 General principles of cosmetic safety evaluation: the industrial perspectives
Catherine Mahoney
Procter & Gamble Technical Centres Limited, Egham, Surrey, UK

11:45 – 12:00 


12:00 – 13:00 

Lunch break
13:00 – 13:45 Application of the TTC concept for cosmetic ingredients
Corrado L. Galli
Laboratory of Toxicology, Università degli Studi di Milano, Italy
13:45 – 14:30

Read across for cosmetic ingredients
Mark Cronin
School of Pharmacy and Biomolecular Sciences Liverpool John Moores University, Liverpool, UK

14:30 – 15:15 In vitro reconstructed 3D models: opportunities for testing cosmetic ingredients and products without animals
Helena Kandarova
MatTek In Vitro Life Science Laboratories, Bratislava, Slovak Republic
15:15 – 16:00

Implementation of non-animal testing strategies in cosmetic safety evaluation and other chemical frameworks
Jos Bessems
Independent expert 'toxicokinetics in risk assessment', The Netherlands

16:00 – 16:15 Discussion and Closing of the CE course


Session Abstract

By definition a cosmetic product made available on the market shall be safe for human health when used under normal or reasonably foreseeable conditions of use. The European Cosmetics Directive, however, bans animal tests to evaluate the human safety of cosmetic products and their ingredients, which represents a challenge for new ingredients and for the cosmetic industries. In the era of Tox21, the use of non animal tests are likely to have an increasing impact in future years but for cosmetic products this represents the only option. The aim of this course will be to provide information on current use and perspective on non animal test for the safety evaluation of cosmetic ingredients. Both regulatory and industrial views will be discussed together with new opportunities, e.g. TTC, read across, 3D models and integrated strategies for safety evaluation.


13:45 – 14:30 



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