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CEC 4

Cosmetic safety evaluation in the era of alternatives

Programme of the Session

  • General principles of cosmetic safety evaluation: the SCCS requests
    Gisela H Degen
    Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
  • General principles of cosmetic safety evaluation: the industrial perspectives
    Catherine Mahoney
    Procter & Gamble Technical Centres Limited, Egham, Surrey, UK
  • Application of the TTC concept for cosmetic ingredients
    Corrado L. Galli
    Laboratory of Toxicology, Università degli Studi di Milano, Italy
  • Read across for cosmetic ingredients
    Mark Cronin
    School of Pharmacy and Biomolecular Sciences Liverpool John Moores University, Liverpool, UK
  • In vitro reconstructed 3D models: opportunities for testing cosmetic ingredients and products without animals
    Helena Kandarova
    MatTek In Vitro Life Science Laboratories, Bratislava, Slovak Republic
  • Implementation of non-animal testing strategies in cosmetic safety evaluation and other chemical frameworks
    Jos Bessems
    Independent expert 'toxicokinetics in risk assessment', The Netherlands

Session Abstract

By definition a cosmetic product made available on the market shall be safe for human health when used under normal or reasonably foreseeable conditions of use. The European Cosmetics Directive, however, bans animal tests to evaluate the human safety of cosmetic products and their ingredients, which represents a challenge for new ingredients and for the cosmetic industries. In the era of Tox21, the use of non animal tests are likely to have an increasing impact in future years but for cosmetic products this represents the only option. The aim of this course will be to provide information on current use and perspective on non animal test for the safety evaluation of cosmetic ingredients. Both regulatory and industrial views will be discussed together with new opportunities, e.g. TTC, read across, 3D models and integrated strategies for safety evaluation.
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